Syphilis is a bacterial infection caused by Treponema pallidum and its transmission through blood transfusion poses a considerable risk to transfusion safety. The aim of this study was to assess the prevalence of syphilis among blood donors in Brazzaville, Republic of Congo. This was a cross sectional study conducted from September 2022 to February 2023. Data were collected from the national blood bank in Brazzaville. A structured questionnaire was designed and presented to each donor at the time of sample collection. The demographic data, including age, gender, educational, occupation, marital status and types of donors were routinely collected. During the donation procedure, 5 mL of peripheral blood was collected in a sterile EDTA test tube. All the donor samples were screened by ELISA test. Out of the 2560 blood donors included, 2258 donors (88.2%) were males while 302 (11.8%) were females. The mean age was 32±8.62 years. The overall prevalence of syphilis antibodies was 18 (0.7%). Majority of positive donors were females and in the age group 45-65 years, with a statistically significant correlation (p<0.05). Although, we found a high rate of syphilis carriage among donors in secondary education level, laborer, single and replacement donors, no significant relationship was found (p>0.05). This study provides crucial information on the epidemiology of syphilis among blood donors in Brazzaville and underscores the importance of strengthening screening and prevention strategies among this population.
| Published in | International Journal of Microbiology and Biotechnology (Volume 8, Issue 4) |
| DOI | 10.11648/j.ijmb.20230804.14 |
| Page(s) | 94-97 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2023. Published by Science Publishing Group |
Syphilis, Prevalence, Blood Donors, Brazzaville
| [1] | Mabey D. Epidemiology of STIs: worldwide. Medicine 2005; 33(9): 4-7. |
| [2] | Norris SJ, Cox DL, Weinstock GM. Biology of Treponema pallidum: correlation of functional activities with genome sequence data. Journal of molecular microbiology and biotechnology 2001; 3(1): 37-62. |
| [3] | Kassutto S. HIV and syphilis coinfection: Trends and interactions. AIDS Clinical Care 2003; 15: 9 15. |
| [4] | Rowley J, Vander HS. Korenromp E, Low N, Unemo M, Abu-Raddad LJ, Taylor MM. Chlamydia, gonorrhoea, trichomoniasis and syphilis: global prevalence and incidence estimates, 2016. Bulletin of the World Health Organization 2019; 97(8): 548-562. |
| [5] | Tagny CT. Syphilis and blood safety in developing countries. In Tech 2011: 123-130. |
| [6] | Sarkodie F, Hassall O, Owusu-Dabo E, Owusu-Ofori S, Bates I, Bygbjerg IC, Owusu-Ofori A, Harritshøj LH, Ullum H. Improving the screening of blood donors with syphilis rapid diagnostic test (RDT) and rapid plasma reagin (RPR) in low- and middle-income countries (LMIC). Transfusion Medicine 2017; 27: 52–59. |
| [7] | Tagny CT. Le dépistage biologique de la syphilis chez le donneur de sang d’Afrique subsaharienne: quelle stratégie?. Transfusion clinique et biologique 2009; 16(5-6): 448-453. |
| [8] | Mbongolo NL, Niama FR, Issamou MP, Kombo EB, Nzingoula FK, Mboussou FF, Kobawila SC. Infections à VIH, Syphilis, Hépatites B et C chez les Hommes ayant des Rapports Sexuels avec d’autres Hommes en République du Congo. Health sciences and disease 2019; 20(6): 49-54. |
| [9] | Niama RF, Bongolo NCL, Kombo ESB, Yengo R, Mayengue PI, Kosso EBM, Parra HJ. Syphilis and HIV infections among pregnant women attending antenatal clinics in Republic of Congo. Pan African Medical Journal 2017; 28(1): 1-8. |
| [10] | Biendo M, Yala F. Etude séro-épidémiologique de la syphilis à Brazzaville. Médecine et Maladies Infectieuses 1990; 20(1): 6-8. |
| [11] | Da Ros CT, da Silva Schmitt C. Global epidemiology of sexually transmitted diseases. Asian journal of andrology 2008; 10(1): 110-114. |
| [12] | Ankouane F, Noah DN, Atangana MM, Simo RK, Guekam PR, Sida MB. Séroprévalence des virus des hépatites B et C, du VIH-1/2 et de la syphilis chez les donneurs de sang de l’hôpital central de Yaoundé, région du centre, Cameroun. Transfusion Clinique et Biologique 2016; 23(2): 72-77. |
| [13] | Mayaki Z, Dardenne N, Kabo R, Moutschen M, Sondag D, Albert A, Gérard C. Séroprévalence des marqueurs de l’infection chez les donneurs de sang à Niamey (Niger). Revue d’épidémiologie et de santé publique 2013; 61(3): 233-240. |
| [14] | Bah A, Traoré MK, Kassogué A, Coulibaly D, Sogodogo I, Diallo H, Diallo M. Séroprévalence des donneurs de sang à l'hôpital Nianankoro Fomba de Ségou. Rev Mali Infect Microbiol 2019; 13(1): 41-46. |
| [15] | Batina A, Kabemba S, Malengela R. Marqueurs infectieux chez les donneurs de sang en République Démocratique du Congo (RDC). Revue Medicale de Bruxelles-Nouvelle Serie 2007; 28(3): 145-149. |
| [16] | Doungous DM, Doutoum AA, Chatté A, Dounbe RL, Gabdibe EG, Saleh O, Njintang NY. Prévalence de la syphilis chez les donneurs de sang à la Banque du Sang d’Abéché au Tchad. International Journal of Biological and Chemical Sc 2020; 1085-1092. |
| [17] | Singhal S, Sharma DC, Rai S, Arya A, Gupta P. Seroprevalence and Risk Factors of Syphilis among Blood Donors. Journal of College of Medical Sciences-Nepal 2021; 17(2): 185-194. |
| [18] | Chen X, Liu Q, Sun P, Yuan S, Liao H, Zhang X. Prevalence of Syphilis Infections Among Volunteer Blood Donors in Jinan Blood Center, China: A 15-Year Retrospective Study. Infection and Drug Resistance 2022; 6431-6440. |
| [19] | Zheng X, Ding W, Ling X, Shi J, Dong J, Yu G, Hu W. Prevalence of Treponema Pallidum Antibody among Volunteer Blood Donors in China. Canadian Journal of Infectious Diseases and Medical Microbiology 2022; 2022. |
| [20] | Alharazi T, Alzubiery TK, Alcantara JC, Qanash H, Bazaid AS, Altayar MA, Aldarhami A. Prevalence of transfusion-transmitted infections (HCV, HIV, Syphilis and Malaria) in blood donors: a large-scale cross-sectional study. Pathogens 2022; 11(7): 1-12. |
| [21] | Yesha Shah, Farzana Kothari, Milind Dighe, Chirag Chaudhari. Demographic profile of syphilis among blood donors at a tertiary care hospital. International Journal of Research in Medicine 2018; 7(2): 25-29. |
APA Style
Monic Angounda, B., Oscar Mokono, S., Koukouikila-Koussounda, F., Systeme Lekanga, I., Mbanzoulou Boukatou, G., et al. (2023). Epidemiology of Syphilis Among Blood Donors in Brazzaville, Republic of Congo. International Journal of Microbiology and Biotechnology, 8(4), 94-97. https://doi.org/10.11648/j.ijmb.20230804.14
ACS Style
Monic Angounda, B.; Oscar Mokono, S.; Koukouikila-Koussounda, F.; Systeme Lekanga, I.; Mbanzoulou Boukatou, G., et al. Epidemiology of Syphilis Among Blood Donors in Brazzaville, Republic of Congo. Int. J. Microbiol. Biotechnol. 2023, 8(4), 94-97. doi: 10.11648/j.ijmb.20230804.14
AMA Style
Monic Angounda B, Oscar Mokono S, Koukouikila-Koussounda F, Systeme Lekanga I, Mbanzoulou Boukatou G, et al. Epidemiology of Syphilis Among Blood Donors in Brazzaville, Republic of Congo. Int J Microbiol Biotechnol. 2023;8(4):94-97. doi: 10.11648/j.ijmb.20230804.14
Share This Article
Twitter
Linked In
Facebook
Copy
Download@article{10.11648/j.ijmb.20230804.14,
author = {Brunel Monic Angounda and Serge Oscar Mokono and Felix Koukouikila-Koussounda and Inatan Systeme Lekanga and Geneviève Mbanzoulou Boukatou and Fabien Roch Niama and Alain Vouidibio},
title = {Epidemiology of Syphilis Among Blood Donors in Brazzaville, Republic of Congo},
journal = {International Journal of Microbiology and Biotechnology},
volume = {8},
number = {4},
pages = {94-97},
doi = {10.11648/j.ijmb.20230804.14},
url = {https://doi.org/10.11648/j.ijmb.20230804.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmb.20230804.14},
abstract = {Syphilis is a bacterial infection caused by Treponema pallidum and its transmission through blood transfusion poses a considerable risk to transfusion safety. The aim of this study was to assess the prevalence of syphilis among blood donors in Brazzaville, Republic of Congo. This was a cross sectional study conducted from September 2022 to February 2023. Data were collected from the national blood bank in Brazzaville. A structured questionnaire was designed and presented to each donor at the time of sample collection. The demographic data, including age, gender, educational, occupation, marital status and types of donors were routinely collected. During the donation procedure, 5 mL of peripheral blood was collected in a sterile EDTA test tube. All the donor samples were screened by ELISA test. Out of the 2560 blood donors included, 2258 donors (88.2%) were males while 302 (11.8%) were females. The mean age was 32±8.62 years. The overall prevalence of syphilis antibodies was 18 (0.7%). Majority of positive donors were females and in the age group 45-65 years, with a statistically significant correlation (p0.05). This study provides crucial information on the epidemiology of syphilis among blood donors in Brazzaville and underscores the importance of strengthening screening and prevention strategies among this population.
},
year = {2023}
}
TY - JOUR T1 - Epidemiology of Syphilis Among Blood Donors in Brazzaville, Republic of Congo AU - Brunel Monic Angounda AU - Serge Oscar Mokono AU - Felix Koukouikila-Koussounda AU - Inatan Systeme Lekanga AU - Geneviève Mbanzoulou Boukatou AU - Fabien Roch Niama AU - Alain Vouidibio Y1 - 2023/12/06 PY - 2023 N1 - https://doi.org/10.11648/j.ijmb.20230804.14 DO - 10.11648/j.ijmb.20230804.14 T2 - International Journal of Microbiology and Biotechnology JF - International Journal of Microbiology and Biotechnology JO - International Journal of Microbiology and Biotechnology SP - 94 EP - 97 PB - Science Publishing Group SN - 2578-9686 UR - https://doi.org/10.11648/j.ijmb.20230804.14 AB - Syphilis is a bacterial infection caused by Treponema pallidum and its transmission through blood transfusion poses a considerable risk to transfusion safety. The aim of this study was to assess the prevalence of syphilis among blood donors in Brazzaville, Republic of Congo. This was a cross sectional study conducted from September 2022 to February 2023. Data were collected from the national blood bank in Brazzaville. A structured questionnaire was designed and presented to each donor at the time of sample collection. The demographic data, including age, gender, educational, occupation, marital status and types of donors were routinely collected. During the donation procedure, 5 mL of peripheral blood was collected in a sterile EDTA test tube. All the donor samples were screened by ELISA test. Out of the 2560 blood donors included, 2258 donors (88.2%) were males while 302 (11.8%) were females. The mean age was 32±8.62 years. The overall prevalence of syphilis antibodies was 18 (0.7%). Majority of positive donors were females and in the age group 45-65 years, with a statistically significant correlation (p0.05). This study provides crucial information on the epidemiology of syphilis among blood donors in Brazzaville and underscores the importance of strengthening screening and prevention strategies among this population. VL - 8 IS - 4 ER -
Faculty of Science and Technology, Marien Ngouabi University, Brazzaville, Congo; National Center of Blood Transfusion, Brazzaville, Congo
