Volume 4, Issue 4, December 2019, Page: 75-83
Callus Culture for the Production of Therapeutic Compounds
Emmanuel Dabuwar Benjamin, Department of Pharmaceutical Microbiology and Biotechnology, University of Jos, Jos, Nigeria; Department of Biotechnology, Modibbo Adama University of Technology, Yola, Nigeria
Gali Adamu Ishaku, Department of Pharmaceutical Microbiology and Biotechnology, University of Jos, Jos, Nigeria
Fartisincha Andrew Peingurta, Department of Science Laboratory Technology, Modibbo Adama University of Technology, Yola, Nigeria
Abolade Samuel Afolabi, Biotechnology and Genetic Engineering Advanced Laboratory, Sheda Science and Technology Complex, Abuja, Nigeria
Received: Sep. 20, 2019;       Accepted: Oct. 8, 2019;       Published: Oct. 23, 2019
DOI: 10.11648/j.ajpb.20190404.14      View  26      Downloads  8
Abstract
Plant-derived compounds retain a special place in the treatment of various diseases across the world. Their application cuts across every class of disease, where they are found to be often equal or of greater potency, safer and cheaper than so-called "orthodox" medicines. These advantages have led to great interest in the use of callus culture as a biotechnological tool for the harnessing of these useful therapeutic compounds. Callus culture techniques aim to increase the yield of active constituents in cultured plant cells and to produce novel products on a large scale. These techniques have been applied to produce various classes of therapeutic compounds from diverse plant species through empirical determination of ideal culture conditions and other methods. This review presents at a glance the recent advances being made in the field of callus culture for the production of therapeutic compounds, with the aim of showing that it is time for the full potentials of callus culture to be exploited on a scale that will prove a useful weapon in the arsenal of clinical therapeutics.
Keywords
Callus Culture, Plant Growth Regulator, Elicitor, Precursor, Anticancer, Antiviral, Antioxidant, Therapeutic Nanoparticles
To cite this article
Emmanuel Dabuwar Benjamin, Gali Adamu Ishaku, Fartisincha Andrew Peingurta, Abolade Samuel Afolabi, Callus Culture for the Production of Therapeutic Compounds, American Journal of Plant Biology. Vol. 4, No. 4, 2019, pp. 75-83. doi: 10.11648/j.ajpb.20190404.14
Copyright
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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